Targeting serious diseases of
immuno-inflammation and fibrosis
Our lead product candidate cenicriviroc (CVC) is under evaluation to treat non-alcoholic steatohepatitis (NASH) with liver fibrosis and other serious illnesses
NASH is a severe type of non-alcoholic fatty liver disease, or NAFLD. NASH affects 3 to 5 percent of the US population and can lead to life-threatening complications such as cirrhosis and liver cancer. There are no approved therapies for patients suffering from this severe condition.
Tobira is evaluating CVC’s efficacy and safety in multiple clinical studies, including the CENTAUR Study, an international, randomized Phase 2b study of CVC vs placebo in patients with NASH and liver fibrosis (NCT02217475).
NASH and Supporting Clinical Studies
- 2.9.16 Tobira Therapeutics Completes Patient Recruitment for ORION Phase 2a Study of Cenicriviroc in Obese Patients with Suspected Fatty Liver Disease
- 2.1.16 Tobira Therapeutics to Participate in Two Conferences in February
- 1.7.16 Tobira Therapeutics Announces Initiation of Program to Evaluate Cenicriviroc for the Treatment of Primary Sclerosing Cholangitis